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Monoclonal antibody , Recombinant protein

Monoclonal antibodies are immunoglobulins produced by plasma cells differentiated from B lymphocytes under the stimulation of antigens by the immune system of the body, which can specifically bind to the corresponding antigens. Recombinant protein is a recombinant vector obtained by inserting a DNA/RNA gene fragment that can be translated into a target protein into a host cell, which can express the target protein by the use of gene recombination technology. With the characteristics of high specificity and definitive efficacy, monoclonal antibodies and recombinant protein drugs have shown unique advantages and made great progress in the fields of tumor, autoimmunity, metabolism, viral infection and other diseases, which are one of the fastest growing and strongest competitive tracks in medicine. Membrane filtration plays an important role in the production of monoclonal antibodies and recombinant protein drugs, including clarification of cell culture, removing bacteria from medium, buffer and final formulation, bioburden reduction of intermediate products, and gas filtration during fermentation process.